Johns Hopkins study documents medical errors are third-leading cause of death in U.S.

Johns Hopkins study documents medical errors are third-leading cause of death in U.S.


Martin Makary, MD, PhD. and Robert Gorter, MD, PhD.


Analyzing medical death rate data over an eight-year period, Johns Hopkins patient safety experts have calculated that between 240,000 and 440,000 deaths per year are due to preventable medical error in the U.S.A. alone. Thus; doctors and adjacent staff are directly responsible for these iatrogenic deaths.

Medical definition of iatrogenesis: inadvertent and preventable induction of disease or life-threatening complications by the medical treatment or procedures of a physician or surgeon.

Their figure, published May 3, 2016, in The BMJ, surpasses the U.S. Centers for Disease Control and Prevention’s third leading cause of death—respiratory disease, which kills close to 150,000 people per year.

The Johns Hopkins team says the CDC’s way of collecting national health statistics fails to classify medical errors separately on the death certificate. The researchers are advocating for updated criteria for classifying deaths on death certificates.

“Incidence rates for deaths directly attributable to medical care gone awry haven’t been recognized in any standardized method for collecting national statistics,” says Martin Makary, professor of surgery at the Johns Hopkins University School of Medicine and an authority on health reform. “The medical coding system was designed to maximize billing for physician services, not to collect national health statistics, as it is currently being used.”

In 1949, Makary says, the U.S. adopted an international form that used International Classification of Diseases billing codes to tally causes of death.

“At that time, it was under-recognized that diagnostic errors, medical mistakes, and the absence of safety nets could result in someone’s death,” says Makary, “and because of that, medical errors were unintentionally excluded from national health statistics.”

In their study, the researchers examined four separate studies that analyzed medical death rate data from 2000 to 2008. Then, using hospital admission rates from 2013, they extrapolated that based on a total of 35,416,020 hospitalizations, 251,454 deaths stemmed from a medical error, which the researchers say now translates to 9.5 percent of all deaths each year in the U.S.


Martin Makary, professor of surgery at Johns Hopkins

According to the CDC, in 2013, 611,105 people died of heart disease, 584,881 died of cancer, and 149,205 died of chronic respiratory disease—the top three causes of death in the U.S. The newly calculated figure for medical errors puts this cause of death behind cancer but ahead of respiratory disease.

“Top-ranked causes of death as reported by the CDC inform our country’s research funding and public health priorities,” Makary says. “Right now, cancer and heart disease get a ton of attention, but since medical errors don’t appear on the list, the problem doesn’t get the funding and attention it deserves.”

The researchers caution that most medical errors aren’t due to inherently bad doctors, and that reporting these errors shouldn’t be addressed by punishment or legal action. Rather, they say, most errors represent systemic problems, including poorly coordinated care, fragmented insurance networks, the absence or underuse of safety nets, and other protocols, in addition to unwarranted variation in physician practice patterns that lack accountability.

“Unwarranted variation is endemic in health care,” Makary says. “Developing consensus protocols that streamline the delivery of medicine and reduce variability can improve quality and lower costs in health care. More research on preventing medical errors from occurring is needed to address the problem.”

Dr Robert Gorter

Robert Gorter, MD, PhD. Emeritus Professor University of California San Francisco Medical School (UCSF), etc.

Robert Gorter: This year, I am a practicing physician for 50+ years and still going strong (also academically as a clinical professor of Medicine with specializations in Oncology, Immunology and Translational Medicine) and in clinical research.

It is my observation that many colleagues have little to no knowledge of the fatal interactions medications can have leading to medical emergencies and deaths.

Another important reason is the so-called “Standard Care” where patients are considered “cases or numbers accordingly to their diagnoses” and therapies tailored to the individual needs of a patient are considered “risky.” This has to do with the sue-ready society for malpractice in the USA. If a patients dies but was treated according to “standard care” the doctor or hospital cannot be sued.



Leave a Reply

Your email address will not be published. Required fields are marked *